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عمومی::
پیوند میکروبیوتای مدفوع
Faecal microbiota transplantation (FMT), prebiotics and probiotics are the several approaches that have been proposed to constitute an effective preventive treatment for antibiotic-induced dysbiosis and associated adverse effects in healthy human gut microbiome.
Faecal microbiota transplantation (FMT) refers to the transplantation of functional bacteria in the faeces of healthy donors into the gastrointestinal tract of the patient to restore the stability of the intestinal microecology, which subsequently treats diseases associated with disorders of intestinal microorganisms.
Now, FMT has been used experimentally to treat GI diseases including colitis, constipation, IBD, chronic fatigue syndrome, Parkinson's disease and multiple sclerosis by the production of antimicrobials and activation of the immune system of the mucous layer.
FMT was first reported as a novel treatment and was found to be effective against pseudomembranous enterocolitis and C. difficile infection (CDI) in 1958.
The success rate of FMT on CDI patients was found to be over 90% of cases, compared with cure rates of 26-30% with the previous standard of care to antibiotic treatment (Eiseman et al. 1958).
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